QCA (Quantitative Coronary Analysis) is the worldwide accepted standard for assessment of coronary artery dimensions. The QCA workflow can assist in the selection of the optimal balloon and stent. QCA features single vessel and bifurcation analysis including calibration, automatic contour detection and quantification of the severity of stenosis. For 3D QCA please click here.

 Key Product features

  • Obstruction analysis
  • Local Diameter analysis
  • Total Occlusion analysis

QCA for research

QCA can be extended with research functionality. QCA research has specific additional functionality for both single vessel and bifurcation analysis. Drug Eluting Stent (DES) analysis enables the user to evaluate restenosis and edge effects in pre-, post- and follow-up studies. With User Defined Subsegments (UDS), the vessel of interest can be divided in multiple subsegments and the curvature of these subsegments can be determined. UDS can for example be used in studies on biodegradable stents.  With the Bifurcation 6- and 11-Segment Model (BSM) implanted bifurcation stents can be quickly compared in pre-, post- and follow-up studies.

Extra key product features in QCA research

  • Drug Eluting Stent analysis: evaluation of restenosis and edge effects with a dedicated segment model
  • User Defined Subsegment analysis: divide the vessel in multiple subsegments
  • Independent evaluation of multiple segments within one vessel part
  • Dedicated models for bifurcation analysis: 6 and 11 segments

Key Results

  • Minimum Luminal Diameter
  • Reference Diameter
  • % Diameter Stenosis
  • Length stenotic segment
  • Bifurcation angles

Extra Key Results in QCA for research

  • Up to 6 subsegments analysis results
  • Drug Eluting Stent subsegment analysis results
  • Results of evaluation of auto subsegment analysis
  • 6 and 11 subsegment analysis for bifurcation vessels

Key Publications

  • Hildick Smith D et al. The EBC TWO Study (European Bifurcation Coronary TWO). Catheterization and Cardiovascular Interventions 2016.
  • Akasaka T et al. Angiographic, optical coherence tomography and histology findings from combination of a drug-coated balloon with an everolimus-eluting stent in a porcine model International Journal of Cardiology 2016; 223, 665–668
  • Ishibashi Y, Grundeken MJ, Nakatami S. In vitro validation and comparison of different software packages or algorithms for coronary bifurcation analysis using calibrated phantoms: Implications for clinical practice and research of bifurcation stenting. Catheterization and Cardiovascular Interventions Jul 2014
  • Gronenschild E. High-precision On-Line Quantitative Cardiovascular Analysis with CAAS II. Poster presentation, 5th symposium for coronary angiography, June 1993, Rotterdam
  • Haase J, Escaned J, Montauban van Swijndregt E, Ozaki Y, Gronenschild E, Slager CJ, Serruys PW. Experimental Validation of Geometric and Densitometric Coronary Measurements on the New Generation Cardiovascular Angiography Analysis System (CAASII). Catheterization and Cardiovascular Diagnosis 1993; 30: 104-114
  • Gronenschild E, Janssen J, Tijdens F. CAAS II: A Second Generation system for Off-Line and On-Line Quantitative Coronary Angiography. Catheterization and Cardiovascular Diagnosis 1994; 33: 61-75
  • Ramcharitar S, Onuma Y, Aben JP, Consten C, Weijers B, Morel MA, Serruys PW. A novel dedicated quantitative coronary analysis methodology for bifurcation lesions. Eurointervention 2008; 3:553-557
  • Girasis C, Schuurbiers JC, Onuma Y, Aben JP, Weijers B, Boersma E, Wentzel JJ, Serruys PW. Two-dimensional quantitative coronary angiographic models for bifurcation segmental analysis: In vitro validation of CAAS against precision manufactured plexiglas phantoms.  Catheter. Cardiovasc. Interv. 2010 Oct 11